View primary antibody

Basic data

PIDprimary-0158
EPIC PIDhttps://hdl.handle.net/21.11124/primary-0158
Research groupRG Fernandez-Busnadiego
Quality (mean)no score (0.00)
Sharing levelPublic

Antibody data

Antigen symbolCASP3
Antibody Registry ID(s)AB_2341188
NameCleaved Caspase-3 (Asp175) Antibody
Alternative name
Lab ID
Tag / Fluorophore
Raised inRabbit
Reacts withHuman, Mouse, Rat, Monkey
Clone
Isotype
Clonalitypolyclonal
Demaskingunknown
AntigenCleaved Caspase-3 (Asp175) Antibody detects endogenous levels of the large fragment (17/19 kDa) of activated caspase-3
Crafted Bycompany
Company / ManufacturerCell Signaling Technology
Catalog no.9661S
Lot no.
DescriptionWestern Blotting 1:1000 Immunoprecipitation 1:100 Immunohistochemistry (Paraffin) 1:400 Immunofluorescence (Immunocytochemistry) 1:400 Flow Cytometry 1:800
Localization
Storage instructionStore at –20°C. Do not aliquot the antibody.
Receipt date2021-02-04 00:00:00
Preparation date2021-02-04 00:00:00
Created byKlauenberg, Vanessa
Last modifiedKlauenberg, Vanessa

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Linked publications


Amyloid-like aggregates cause lysosomal defects in neurons via gain-of-function toxicity
Schaefer T, Riera-Tur I, Hornburg D, Mishra A, Fernández-Mosquera L, Raimundo N, Mann M, Baumeister W, Klein R, Meissner F, Fernández-Busnadiego R, Dudanova I
bioRxiv 2019 : 10.1101/2019.12.16.877431

Stress- and ubiquitylation-dependent phase separation of the proteasome
Yasuda S, Tsuchiya H, Kaiho A, Guo Q, Ikeuchi K, Endo A, Arai N, Ohtake F, Murata S, Inada T, Baumeister W, Fernández-Busnadiego R, Tanaka K, Saeki Y
Nature 2020 : 10.1038/s41586-020-1982-9

Amyloid-like aggregating proteins cause lysosomal defects in neurons via gain-of-function toxicity
Riera-Tur I, Schäfer T, Hornburg D, Mishra A, da Silva Padilha M, Fernández-Mosquera L, Feigenbutz D, Auer P, Mann M, Baumeister W, Klein R, Meissner F, Raimundo N, Fernández-Busnadiego R, Dudanova I
Life Sci Alliance 2021 : 10.26508/lsa.202101185