Technical Support: menoci@medizin.uni-goettingen.de
Department of Medical Informatics
University Medical Center Göttingen
Imprint
View primary antibody
Basic data
| PID | primary-0104 |
| EPIC PID | https://hdl.handle.net/21.11124/primary-0104 |
| Research group | RG Zimmermann |
| Quality (mean) | no score (0.00) |
| Sharing level | Public |
Antibody data
| Antigen symbol | AQP1 |
| Antibody Registry ID(s) | AB_626693 |
| Name | AQP1 (1/22) antibody |
| Alternative name | CHIP28 |
| Lab ID | |
| Tag / Fluorophore | |
| Raised in | Mouse |
| Reacts with | mouse, rat, human |
| Clone | 1/22/2010 |
| Isotype | IgG2b |
| Clonality | monoclonal |
| Demasking | unknown |
| Antigen | against amino acid sequence 249-269 of intracellular AQP1 from the species rat |
| Crafted By | company |
| Company / Manufacturer | Santa Cruz Biotechnology |
| Catalog no. | sc-32737 |
| Lot no. | |
| Description | AQP1 (1/22) is recommended for detection of AQP1 of mouse, rat and humanorigin by Western Blotting (starting dilution 1:200, dilution range 1:100-1:1000), immunoprecipitation [1-2 μg per 100-500 μg of total protein (1 mlof cell lysate)], immunofluorescence (starting dilution 1:50, dilution range1:50-1:500), immunohistochemistry (including paraffin-embedded sections)(starting dilution 1:50, dilution range 1:50-1:500) and flow cytometry (1 μgper 1 x 106cells). |
| Localization | |
| Storage instruction | Store at 4° C, **DO NOT FREEZE**. Stable for one year from the date ofshipment. Non-hazardous. No MSDS required. |
| Receipt date | 2021-01-01 00:00:00 |
| Preparation date | 2021-01-28 00:00:00 |
| Created by | Klauenberg, Vanessa |
| Last modified | Klauenberg, Vanessa |
External links
| Antibodypedia | - |
| HGNC | http://www.genenames.org/cgi-bin/gene_symbol_report?match=AQP1 |
| Wikipedia | http://en.wikipedia.org/wiki/AQP1 |
| Uniprot | http://www.uniprot.org/uniprot/?query=AQP1 |
| GeneCards | http://www.genecards.org/cgi-bin/carddisp.pl?gene=AQP1 |
| Antibody Registry | http://antibodyregistry.org/search?q=AB_626693 |
Applications
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Linked publications
Inhibition of aquaporin-1 prevents myocardial remodeling by blocking the transmembrane transport of hydrogen peroxide
Montiel V, Bella R, Michel LYM, Esfahani H, De Mulder D, Robinson EL, Deglasse J, Tiburcy M, Chow PH, Jonas J, Gilon P, Steinhorn B, Michel T, Beauloye C, Bertrand L, Farah C, Dei Zotti F, Debaix H, Bouzin C, Brusa D, Horman S, Vanoverschelde J, Bergmann O, Gilis D, Rooman M, Ghigo A, Geninatti-Crich S, Yool A, Zimmermann WH, Roderick HL, Devuyst O, Balligand J
Sci Transl Med 2020 : 10.1126/scitranslmed.aay2176
