Technical Support: menoci@medizin.uni-goettingen.de
Department of Medical Informatics
University Medical Center Göttingen
Imprint
View primary antibody
Basic data
| PID | primary-0096 |
| EPIC PID | https://hdl.handle.net/21.11124/primary-0096 |
| Research group | RG Zimmermann |
| Quality (mean) | no score (0.00) |
| Sharing level | Public |
Antibody data
| Antigen symbol | AQP1 |
| Antibody Registry ID(s) | AB_1163380 |
| Name | Anti-Aquaporin 1 Antibody |
| Alternative name | CHIP28 |
| Lab ID | |
| Tag / Fluorophore | |
| Raised in | Rabbit |
| Reacts with | human, rat, mouse |
| Clone | |
| Isotype | |
| Clonality | polyclonal |
| Demasking | unknown |
| Antigen | KLH-conjugated linear peptide corresponding to the topological domain of rat Aquaporin 1. |
| Crafted By | company |
| Company / Manufacturer | Merck Millipore |
| Catalog no. | AB2219 |
| Lot no. | |
| Description | Western Blotting: 1-10 μg/mL using Chemiluminescence technique. Immunoblots reveal two bands, a lower 28 kDa band corresponding to unglycosylated form and an upper high molecular 35-60 kDa glycosylated component (Denker et al. 1988; Smith & Agre 1991) We recommend the use of 0.5-1.0% milk in all primary/secondary antibody-enzyme conjugate incubations in order to suppress non-specific bands. Immunohistochemistry Analysis: A 1:2,000 dilution from a representative lot detected Aquaporin 1 in human kidney and mouse kidney tissue. |
| Localization | |
| Storage instruction | Maintain at 2-8°C in undiluted aliquots for up to 1 year after date of receipt. |
| Receipt date | 2021-01-27 00:00:00 |
| Preparation date | 2021-01-27 00:00:00 |
| Created by | Klauenberg, Vanessa |
| Last modified | Klauenberg, Vanessa |
External links
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Linked publications
Inhibition of aquaporin-1 prevents myocardial remodeling by blocking the transmembrane transport of hydrogen peroxide
Montiel V, Bella R, Michel LYM, Esfahani H, De Mulder D, Robinson EL, Deglasse J, Tiburcy M, Chow PH, Jonas J, Gilon P, Steinhorn B, Michel T, Beauloye C, Bertrand L, Farah C, Dei Zotti F, Debaix H, Bouzin C, Brusa D, Horman S, Vanoverschelde J, Bergmann O, Gilis D, Rooman M, Ghigo A, Geninatti-Crich S, Yool A, Zimmermann WH, Roderick HL, Devuyst O, Balligand J
Sci Transl Med 2020 : 10.1126/scitranslmed.aay2176
